6533b830fe1ef96bd1297c7e

RESEARCH PRODUCT

Leptin and the central control of feeding behavior.

Luc PénicaudSophie MeillonSophie MeillonSophie MeillonLaurent BrondelLaurent BrondelLaurent Brondel

subject

LeptinFood intakemedicine.medical_specialty[ SDV.AEN ] Life Sciences [q-bio]/Food and NutritionControl (management)BiologyBiochemistryEnergy homeostasisFeeding behaviorInternal medicinemedicineAnimalsHomeostasisHumansNeuronsLeptin DeficiencyLeptindigestive oral and skin physiologyGeneral MedicineFeeding BehaviorEndocrinologyHomeostatic systemNerve Net[SDV.AEN]Life Sciences [q-bio]/Food and NutritionBrain circuitryCognitive psychology

description

International audience; The discovery of leptin by Friedman and coll. in 1995 was a major step forward in our comprehensive view of energy homeostasis. Since the original paper, a tremendous amount of work has been performed in laboratories all over the world. Many recent reviews have described this work in details. In the present review, we focus on the role of leptin on food intake. It is accepted by most authors working in this field that the control of food intake can be divided in two closely-related system: the homeostatic system and the hedonic system. Leptin has been shown to act on both systems.

https://hal.archives-ouvertes.fr/hal-00745912