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RESEARCH PRODUCT

Does chlorhexidine improve outcomes in non-surgical management of peri-implant mucositis or peri-implantitis? : a systematic review and meta-analysis

J YuS LiuJ Limiñana-cañal

subject

MucositisPeri-implantitisPeri-implant mucositisMEDLINEDentistryReview03 medical and health sciences0302 clinical medicineMucositismedicineHumansIn patientGeneral DentistryDental ImplantsStomatitisbusiness.industryIncidence (epidemiology)ChlorhexidineChlorhexidine030206 dentistrymedicine.disease:CIENCIAS MÉDICAS [UNESCO]Peri-ImplantitisOtorhinolaryngologyMeta-analysisUNESCO::CIENCIAS MÉDICASSurgerybusinessImplantologymedicine.drug

description

Background With greater number of implants being placed in clinical practice, incidence of peri-implant diseases are on the rise. It is not known whether chlorhexidine (CHX) improves outcomes in the management of peri-implant diseases. The aim of this systematic review and meta-analysis was to evaluate the role of CHX in improving outcomes with non-surgical management of peri-implant mucositis and peri-implantitis. Material and Methods An electronic search of PubMed, Scopus, Embase, and CENTRAL (Cochrane Central Register of Controlled Trials) databases up to 1st August 2019 was carried out to search for studies evaluating the efficacy of CHX for non-surgical management of peri-implant diseases. Results Seven studies were included. Four studies evaluated the role of CHX in peri-implant mucositis and three in peri-implantitis. Oral prophylaxis with mechanical cleansing of implant surface prior to CHX use was carried out in all seven studies. Meta-analysis indicated that use of CHX did not improve probing depths in peri-implant mucositis (SMD= 0.11; 95% CI: -0.16 to 0.38; p=0.42, I2= 0%). Similarly, CHX did not significantly reduce probing depths in patients with peri-implantitis (MD= 1.57; 95% CI: -0.88 to 4.0; p=0.21, I2= 98%). Results on the efficacy of CHX in reducing BOP in peri-implantitis are conflicting. Conclusions Results of our study indicate that adjunctive therapy with CHX may not improve outcomes with non-surgical management of peri-implant mucositis. Conclusions with regards to its role in non-surgical management of peri-implantitis cannot be drawn. There is a need for more homogenous RCTs with large sample size to define the role of CHX in non-surgical management of peri-implant mucositis and peri-implantitis. Key words:Peri-implant disease, disinfection, dental implants, oral hygiene, chlorhexidine.

yearjournalcountryeditionlanguage
2019-12-14
https://hdl.handle.net/10550/77188