6533b831fe1ef96bd1298da7
RESEARCH PRODUCT
Änderungen des Elektrolytgehaltes von Erythrozyten und Plasma bei nephrektomierten Ratten
G. PetersH. BrunnerG. KuschinskyO. Münchowsubject
Pharmacologymedicine.medical_specialtyChemistrymedicine.medical_treatmentPotassiumchemistry.chemical_elementCell BiologyNephrectomyCellular and Molecular NeuroscienceEndocrinologySerum potassiumBiochemistryInternal medicinemedicineMolecular MedicineBlood corpusclesMolecular Biologydescription
After two-stage nephrectomy in rats the potassium concentration in the red blood corpuscles (RBC) decreases from 10.6 ± 0.3 to 5.5 ± 0.3 mEq per 100 ml of RBC within 48 h. The decrease is accompanied by a much smaller increase in the plasma potassium concentration; the hyperkaliemia in nephrectomized rats is less pronounced than in nephrectomized dogs or anuric humans. Na+ in RBC increases by about 44% after nephrectomy; while there is only a very slight decrease of Na+ in plasma. Plasma chlorides drop from 10.92 ± 0.08 mEq/100 ml of plasma to 6.00 ± 0.81 mEq % within 48 h after nephrectomy. RBC chlorides tend to increase again after an initial drop from 5.22 ± 0.07 to 3.82 ± 0.90 mEq% within the first 8 h.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1957-02-01 | Experientia |