6533b831fe1ef96bd1298dd0

RESEARCH PRODUCT

Prescription of automatic bilevel ventilation (AutoBI) in sleep-disordered breathing: analysis according to diagnosis and occurrence of comorbidities

Maria R. BonsignoreAlessandra CastrogiovanniEmilia MazzucaClaudia I. Gruttad'auriaPierpaolo Baiamonte

subject

medicine.medical_specialtyPediatricsbusiness.industryNocturnal hypoventilationSevere obesitynervous system diseasesrespiratory tract diseasesBreathingmedicineSleep disordered breathingIn patientMedical prescriptionIntensive care medicinebusiness

description

CPAP is the first-choice treatment for obstructive sleep-disordered breathing (O-SDB), while the criteria to prescribe AutoBI are undefined. Trials of AutoBI ventilation in patients (pts) treated for O-SDB from January 2015 to October 2016 (64 out of 242 titrations) were reviewed to assess: a) the clinical characteristics of these pts, b) the reason to shift from CPAP to AutoBI, c) the compliance to prescribed treatment. AutoBI was used in cases of intolerance to high therapeutic CPAP levels (n=21) or incomplete resolution of SDB on CPAP (n=43). The Table reports the differences between CPAP or AutoBI pts CPAP SDB diagnosis was: 82% OSA, 18% OSA-COPD Overlap in the CPAP group; 39% OSA, 28% OSA-COPD Overlap and 33% OHS in the AutoBI group (p In conclusion, AutoBi can be considered an effective and well-tolerated treatment in pts with obstructive SDB, especially in cases with severe obesity, nocturnal hypoventilation, or needing high therapeutic pressures.

https://doi.org/10.1183/23120541.sleepandbreathing-2017.p21