6533b831fe1ef96bd1298de8
RESEARCH PRODUCT
Adult Neurogenesis in Reptiles
José Manuel García-verdugoMelissa LezametaSusana González-granerosubject
Glial fibrillary acidic proteinNeurogenesisBiologyOlfactory bulbLateral ventriclesmedicine.anatomical_structurenervous systemNeuroblastParenchymamedicinebiology.proteinSomaNeuroscienceGliogenesisdescription
Adult neurogenesis in reptiles is a well-documented phenomenon and exists in many telencephalic areas. The newly generated neurons originate along the walls of the lateral ventricles, mainly in the sulci. The putative neural progenitors are radial glial cells. These glial cells give rise to neuroblasts that migrate to their final destination. In general, the new neurons are born in the portion of the ventricular zone (VZ) adjacent to the telencephalic area where they will be recruited and migrate radially through the brain parenchyma along the processes of radial glial cells to their final destination, although migration to the olfactory bulbs (OB) is different. Specifically, it seems that new neurons of the OB are not produced in the ventricular walls of the OB ventricle, but instead in more caudal levels of the lateral ventricles. They then migrate tangentially over the soma of the VZ radial glia until they reach the OB. Adult neurogenesis creates microneurons and projection neurons, and occasionally there is gliogenesis as well.
year | journal | country | edition | language |
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2011-01-01 |