6533b831fe1ef96bd129905a
RESEARCH PRODUCT
Topology testing of phylogenies using least squares methods
Borys WróbelBorys WróbelAleksandra CzarnaRafael SanjuánFernando González-candelassubject
EvolutionInverseHepacivirusBiologyTopologyDNA MitochondrialLeast squares methodsLeast squaresEvolution MolecularGoodness of fit:CIENCIAS DE LA VIDA::Genética ::Ingeniería genética [UNESCO]Test statisticQH359-425AnimalsHumansLeast-Squares AnalysisPhylogenyEcology Evolution Behavior and SystematicsStatisticPhylogenetic treeCovariance matrixUNESCO::CIENCIAS DE LA VIDA::Genética ::Ingeniería genéticaMethodology ArticlePhylogenies; Least squares methodsClassificationHepatitis CTree (graph theory)Sea UrchinsPhylogeniesdescription
[Background] The least squares (LS) method for constructing confidence sets of trees is closely related to LS tree building methods, in which the goodness of fit of the distances measured on the tree (patristic distances) to the observed distances between taxa is the criterion used for selecting the best topology. The generalized LS (GLS) method for topology testing is often frustrated by the computational difficulties in calculating the covariance matrix and its inverse, which in practice requires approximations. The weighted LS (WLS) allows for a more efficient albeit approximate calculation of the test statistic by ignoring the covariances between the distances.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2006-12-01 |