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RESEARCH PRODUCT

Isolation and identification of an antiinflammatory principle from santolina chamaecyparissus

José-luis RíosA. M. VillarRosa-maría Giner

subject

PharmacologySantolina chamaecyparissusbiologyTraditional medicineChemistrybiology.organism_classificationED50

description

The chloroform extract from Santolina chamaecyparissus squarrosa exhibited a potent anti-inflammatory effect on carrageenan-induced oedema in the rat hind paw. β-Sytosteryl 3-β-D-glucoside, isolated by fractionating this extract, was anti-inflammatory in the above test, with intraperitoneal and oral ED50 values of 70 and 146 mg/kg, respectively.

https://doi.org/10.1002/ptr.2650030513