The Role of Vitamin K in Bone Remodeling and Osteoporosis

6533b831fe1ef96bd1299b78

RESEARCH PRODUCT

The Role of Vitamin K in Bone Remodeling and Osteoporosis

Gaetano Leto Maurizio La Guardia Danila Di Majo Marco Giammanco Carla Flandina Melania Di Piazza

subject

Calcium metabolism medicine.medical_specialty Bone density business.industry Osteoporosis chemistry.chemical_element Calcium medicine.disease Bone tissue Settore BIO/09 - Fisiologia Bone remodeling Fat-Soluble Vitamin Endocrinology medicine.anatomical_structure chemistry Internal medicine medicine vitamin K bone metabolism glutamic acid osteocalcin osteoporosis business Homeostasis

description

Vitamin K is an essential fat soluble vitamin involved in the regulation of normal coagulation. However, growing evidence highlights that this molecule appears to be also implicated in the regulation of other important biological functions such as bone mineralization, calcium homeostasis, apoptosis, cell growth and signal transduction. In particular, many studies have focused their attention on the protective effects of vitamin K on bone tissue in the outlook of its use in the prevention and treatment of osteoporosis in post-menopausal women. The objective of the present paper is to review data of the literature regarding the metabolic effects of Vitamin K in bone tissue and its clinical role in the prevention and treatment of osteoporosis.

year	journal	country	edition	language
2012-10-26	Journal of Food Research

https://doi.org/10.5539/jfr.v1n4p106

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