6533b831fe1ef96bd1299b87

RESEARCH PRODUCT

CO-releasing binuclear rhodium complexes as inhibitors of nitric oxide generation in stimulated macrophages.

Ramón Martínez-máñezMajosé AlcarazMaría E. MoraguesRita BrinesFélix SancenónMacarmen Terencio

subject

StereochemistryAnti-Inflammatory Agentschemistry.chemical_elementApoptosisNitric OxideModels BiologicalNitric oxideRhodiumCell LineInorganic Chemistrychemistry.chemical_compoundQUIMICA ORGANICACoordination ComplexesQUIMICA ANALITICAMacrophageMoleculeAnimalsHumansRhodiumPhysical and Theoretical ChemistryCarbon monoxideCarbon MonoxideMacrophagesRegulatorQUIMICA INORGANICAMoleculesHeme oxygenaseHeme oxygenaseCormschemistrySmooth muscle cellsCell cultureApoptosisBiological AssayCarbon monoxide

description

Nontoxic CO-releasing dirhodium complexes act as inhibitors of NO in stimulated macrophage cells, suggesting that novel antiinflammatory treatments could involve the use of these types of binuclear complexes.

yearjournalcountryeditionlanguage
2013-11-27Inorganic chemistry
10.1021/ic401967ghttps://pubmed.ncbi.nlm.nih.gov/24279454