6533b832fe1ef96bd129a1aa

RESEARCH PRODUCT

O2Transport in Skeletal Muscle: Development of Concepts and Current State

Karlfried Groebe

subject

Longitudinal diffusionmedicine.anatomical_structureChemistryStimulation ratemedicineBiophysicsSkeletal muscleFunctional capillary densityCurrent (fluid)

description

When comparing oxygen consumption rates(V O2) of various organs — as shown in Fig. 1 —skeletal muscle is exceptional in two respects: Its consumption rate attains the second largest absolute value of all organs and may vary between rest (0.2 mlO 2.100g-1’• min -1 ) and maximum performance (16 m1O 2.100g-1 • min -1 for electrical stimulation) by a factor of 80, thus covering a range that is by far larger than in any other tissue. In order to understand muscle O 2 transport one has to identify transport mechanisms and evaluate their importance towards bringing about the observed high O 2 fluxes and allowing for their enormous variability.

https://doi.org/10.1007/978-1-4615-2468-7_3