6533b832fe1ef96bd129a2c9

RESEARCH PRODUCT

MOESM3 of Histone macroH2A1.2 promotes metabolic health and leanness by inhibiting adipogenesis

Valerio PazienzaConcetta PanebiancoFrancesca RappaDomenico MemoliMichela BorghesanSara CannitoAsami OjiGiuseppe MazzaDomenico TamburrinoGiuseppe FusaiRosario BaroneGiulia BolascoFrancesc VillarroyaJoan VillarroyaKiyotaka HatsuzawaFrancesco CappelloRoberta TaralloTomoko NakanishiManlio Vinciguerra

subject

description

Additional file 3. Figure S2. Increased glucose clearance because of enhanced insulin sensitivity in the muscle, liver and adipose tissue. Mice fed a chow diet were injected with insulin (INS, 0.75 U kg − 1) 15 min before being killed, after which phosphorylation status of AKT (Ser473) was determined by western blot. Representative immunoblots are shown in the skeletal muscle, liver and adipose tissue. Immunoblots were quantified by densitometry and normalized against total protein levels of AKT. *P

https://dx.doi.org/10.6084/m9.figshare.c.3605930_d4