6533b832fe1ef96bd129a4b3
RESEARCH PRODUCT
Formation rates and protonation constants of azo dyes in a sodium dodecylsulphate micellar solution.
M.c.garcía Alvarez-coqueG.ramis RamosJ.s.esteve Romerosubject
chemistry.chemical_classificationDiazonium CompoundsSodiumInorganic chemistrychemistry.chemical_elementProtonationmacromolecular substancesDosage formAnalytical ChemistryIonchemistry.chemical_compoundAnilinechemistryMoleculeProtonation constantdescription
The effects of a sodium dodecylsulphate micellar solution on the coupling rates of several diazotizated arylamines with N-(1-naphthyl)-ethylenediamine and the shifts in the protonation constants of the corresponding azo dyes are quantitatively studied. Aniline, o-, m- and p-aminobenzoic acids, ethyl p-aminobenzoate and several sulphadrugs are used, and the relationships among the intensity of the effects and the molecular structure of the diazonium ions and the dyes are discussed. A single simplified procedure for the determination of all the substances at pH = 1.3 +/- 0.3, where coupling is quickly completed to directly produce the protonated form of the dyes, is established and applied to the analysis of several pharmaceutical preparations.
year | journal | country | edition | language |
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1991-11-01 | Talanta |