6533b832fe1ef96bd129ad56
RESEARCH PRODUCT
The organization, localization and nucleotide sequence of the histone genes of the midge Chironomus thummi.
Thomas HankelnErwin R. Schmidtsubject
animal structuresMolecular Sequence DataRestriction MappingChironomidaeHistone H4HistonesHistone H3Histone H1Species SpecificityHistone H2AGeneticsHistone H2BAnimalsAmino Acid SequenceCodonPeptide sequenceGenetics (clinical)Repetitive Sequences Nucleic AcidGeneticsbiologyBase SequencefungiNucleic acid sequenceDNAHistoneDrosophila melanogasterbiology.proteindescription
Several histone gene repeating units containing the genes for histones H1, H2A, H2B, H3 and H4 were isolated by screening a genomic DNA library from the midge Chironomus thummi ssp. thummi. The nucleotide sequence of one complete histone gene repeating unit was determined. This repeating unit contains one copy of each of the five histone genes in the order and orientation mean value of H3 H4 mean value of H2A H2B H1 mean value of. The overall length is 6262 bp. The orientation, nucleotide sequence and inferred amino acid sequence as well as the chromosomal arrangement and localization are different from those reported for Drosophila melanogaster. The codon usage also shows marked differences between Chironomus and Drosophila. Thus the histone gene structure reported for Drosophila is not typical of all insects.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1991-10-01 | Chromosoma |