New Cathepsin Inhibitors to Explore the Fluorophilic Properties of the S 2 Pocket of Cathepsin B: Design, Synthesis, and Biological Evaluation

6533b832fe1ef96bd129ad92

RESEARCH PRODUCT

New Cathepsin Inhibitors to Explore the Fluorophilic Properties of the S 2 Pocket of Cathepsin B: Design, Synthesis, and Biological Evaluation

Joaquín Timoneda Michael Gütschow F. Javier Cañada Luis P. Calle Vanessa Rodrigo Jesús Jiménez-barbero Carlos Del Pozo María Sánchez-roselló Santos Fustero Mihiret T. Sisay Jürgen Bajorath Maxim Frizler

subject

Hydrocarbons Fluorinated Stereochemistry Stereoisomerism hydrolases stereoselectivity Catalysis Cathepsin B Cathepsin B Nitriles inhibitors Combinatorial Chemistry Techniques Humans Molecule fluorinated ligands Biological evaluation Cathepsin Molecular Structure Combinatorial Chemistry Techniques ligands Chemistry Organic Chemistry Stereoisomerism Dipeptides General Chemistry fluorinated fluorinated Design synthesis Drug Design peptides Stereoselectivity

description

5 páginas, 1 figura, 2 tablas -- PAGS nros. 5256-5260

year	journal	country	edition	language
2011-01-01	Chemistry – A European Journal

https://doi.org/10.1002/chem.201100113

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