6533b832fe1ef96bd129aecc
RESEARCH PRODUCT
The diagnostic performance of renal function-adjusted D-dimer testing in individuals suspected of having venous thromboembolism
Heidrun LamparterHeidrun LamparterPhilipp S. WildThomas MünzelM. Iris HermannsChristine Espinola-kleinNatalie ArnoldLisa EggebrechtMarkus NaglerMarina Panova-noevaHugo Ten CateHugo Ten CateJürgen H. ProchaskaKarl J. LacknerVincent Ten CateVincent Ten CateMartin H. Prinssubject
AdultMalemedicine.medical_specialtyComputed Tomography AngiographyRenal functionSensitivity and SpecificityFibrin Fibrinogen Degradation Products03 medical and health sciences0302 clinical medicineText miningInternal medicineD-dimermedicineFalse positive paradoxHumansFalse Positive ReactionsProspective StudiesRenal InsufficiencyProspective cohort studyOnline Only ArticlesComputed tomography angiographyAgedProbabilityVenous Thrombosismedicine.diagnostic_testbusiness.industryHematologyVenous ThromboembolismMiddle AgedCardiologyFemalebusinessPulmonary EmbolismVenous thromboembolismAlgorithms030215 immunologyGlomerular Filtration Ratedescription
Renal impairment, a source of chronic hypercoagulability[1][1] and inflammation,[2][2] is known to reduce the specificity of the D-dimer test in the diagnosis of venous thromboembolism (VTE).[3][3] This leads to many false positives in such patients and consequently to additional costs, as well as
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2019-08-31 | Haematologica-the Hematology Journal |