6533b833fe1ef96bd129b67d
RESEARCH PRODUCT
SYNTHESIS AND REARRANGEMENT OFN-METHYL-N-(2-THIAZOLYL)-NITRAMINE
Zdzisław DaszkiewiczJanusz B. KyziołMonika Koterzynasubject
chemistry.chemical_compoundNitratechemistryProduct (mathematics)NitrationOrganic ChemistryMethylationMedicinal chemistryCombinatorial chemistrySodium hydridedescription
Methylation of N-(2-thiazolyl)-nitramine in alkaline solution gives 1,2-dihydro-3-methyl-2-nitriminothiazole which rear-ranges in concentrated sulphuric acid yielding small amount of 2-(N-methylamino)-5-nitrothiazole, identical with the product of rearrangement of N-methyl-N-(2-thiazolyl)-nitramine. The latter compound was obtained by the action of sodium hydride on 2-(N-methylamino)-thiazole followed by the nitration with n-butyl nitrate.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2001-01-01 | Synthetic Communications |