6533b833fe1ef96bd129b704
RESEARCH PRODUCT
Inhibitors of antibiotic resistance mechanisms: clinical applications and future perspectives
Girolamo CirrincionePatrizia DianaBarbara ParrinoDaniela CarboneStella Cascioferrosubject
Pharmacologymedicine.medical_specialtyantibiotic resistanceBacteriaChemistryantivirulence strategyDrug Resistance MicrobialMicrobial Sensitivity TestsAnti-Bacterial Agentsanti-biofilm agentAntibiotic resistanceDrug DiscoveryESKAPE pathogensmedicineMolecular MedicineIntensive care medicinedescription
Bacterial strains responsible for antibiotic resistant infections are increasing in an alarming way and the evolution of resistance mechanisms seems to be unstoppable. In the past decade, many efforts have been made in order to counteract this phenomenon but very few compounds have reached clinical trials. The development of new classes of antibiotics able to overcome the main bacterial drug resistance mechanisms is urgently required to counter the imminent danger of a postantibiotic era.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2020-03-01 |