6533b833fe1ef96bd129b8b9
RESEARCH PRODUCT
Catalytic aerobic oxidative decarboxylation of α-trifluoromethyl-α-hydroxy acids to trifluoromethyl ketones
Rafael RuizAlicia Marco‐aleixandreGonzalo BlayBelen MonjeJosé R. PedroIsabel Fernándezsubject
TrifluoromethylChemistryDecarboxylationOrganic Chemistrychemistry.chemical_elementGeneral MedicineMedicinal chemistryBiochemistryCatalysischemistry.chemical_compoundDrug DiscoveryOrganic chemistryCobaltOxidative decarboxylationdescription
Abstract The oxidative decarboxylation of α-trifluoromethyl-α-hydroxy acids to trifluoromethyl ketones is carried out under mild catalytic aerobic conditions using a cobalt(III) complex in the presence of pivalaldehyde.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2003-03-11 | Tetrahedron |