6533b833fe1ef96bd129b8e5

RESEARCH PRODUCT

Proteomics in ocular fluids

Stephanie C. JoachimFranz H. GrusNorbert Pfeiffer

subject

medicine.medical_specialtygenetic structuresbusiness.industryClinical BiochemistryGlaucomaAqueous humorDiabetic retinopathyMacular degenerationmedicine.diseaseProteomicseye diseasesOphthalmologymedicineTearssense organsbusinessUveitis

description

The focus of this article is to review recent techniques in proteomic analysis of ocular fluids. These fluids include tears, aqueous humor, and vitreous, they will also be compared to serum analysis. Furthermore, we attempt to summarize some disease correlated biomarkers in ocular fluids that were discovered through different proteomic techniques in eye diseases like dry eye, glaucoma, age-related macular degeneration, uveitis, or diabetic retinopathy. This review is trying to point out the importance of these biomarkers for clinical applications.

https://doi.org/10.1002/prca.200700105