EGFP Reporters for Direct and Sensitive Detection of Mutagenic Bypass of DNA Lesions

6533b833fe1ef96bd129c14a

RESEARCH PRODUCT

EGFP Reporters for Direct and Sensitive Detection of Mutagenic Bypass of DNA Lesions

Andriy Khobta Daria Kim Marta Rodriguez-alvarez

subject

DNA Repair Transcription Genetic DNA damage Mutant Genetic Vectors Green Fluorescent Proteins lcsh:QR1-502 host cell reactivation (HCR)Biochemistry Article lcsh:Microbiology 03 medical and health sciences chemistry.chemical_compound mutation assay 0302 clinical medicine translesion synthesis (TLS)transcriptional mutagenesis Transcription (biology)Genes Reporter Humans Cloning Molecular Molecular Biology enhanced green fluorescent protein (EGFP)Polymerase Cells Cultured DNA damage tolerance 030304 developmental biology 0303 health sciences biology DNA synthesis Chemistry Point mutation reporter assay RNA Cell biology Amino Acid Substitution Mutagenesis 030220 oncology & carcinogenesis Mutation biology.protein DNA damage DNA HeLa Cells damage bypass

description

The sustainment of replication and transcription of damaged DNA is essential for cell survival under genotoxic stress

year	journal	country	edition	language
2020-06-13	Biomolecules

10.3390/biom10060902 http://dx.doi.org/10.3390/biom10060902

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