6533b833fe1ef96bd129c34d

RESEARCH PRODUCT

Characterization of a Cu/Zn Superoxide dismutase-encoding gene region in Drosophila willistoni

Douglas SkareckyJan KwiatowskiAmparo LatorreAmparo LatorreFrancisco J. Ayala

subject

GeneticsBase SequencebiologyPolyadenylationSuperoxide DismutaseMolecular Sequence DataIntronDNAGeneral Medicinebiology.organism_classificationMolecular biologyDrosophila virilisOpen Reading FramesExonGeneticsMelanogasterAnimalsCoding regionDrosophilaDrosophila willistoniAmino Acid SequenceGene

description

A Cu/Zn superoxide dismutase-encoding gene (Sod) from Drosophila willistoni was cloned and sequenced. The gene shows a typical structure for a fruit-fly Sod gene, with a coding region of 462 bp in two exons separated by a 417-bp intron. Comparison of the Sod sequences from D. willistoni and D. melanogaster suggests that these species are only remotely related. Downstream from the Sod gene, there is an ORF on the opposite strand that putatively encodes the last exon of an unidentified gene. The polyadenylation signals of the two genes are separated by only 61 bp in D. willistoni, conforming to the common picture of compact dipteran genomes.

https://doi.org/10.1016/0378-1119(94)90085-x