Susceptibility to Heart Defects in Down Syndrome Is Associated with Single Nucleotide Polymorphisms in HAS 21 Interferon Receptor Cluster and VEGFA Genes

6533b834fe1ef96bd129cdff

RESEARCH PRODUCT

Susceptibility to Heart Defects in Down Syndrome Is Associated with Single Nucleotide Polymorphisms in HAS 21 Interferon Receptor Cluster and VEGFA Genes

Letizia Scola Claudia Leonarda Ammoscato Rosa Maria Giarratana Tiziana Fragapane Domenico Lio Maria Piccione Carmela Rita Balistreri

subject

0301 basic medicine VEGFA Adult Heart Defects Congenital Male Vascular Endothelial Growth Factor A Down syndrome lcsh:QH426-470 Adolescent Chromosomes Human Pair 21 Down syndrome SNP Single-nucleotide polymorphism Biology Polymorphism Single Nucleotide Article 03 medical and health sciences Heart disorder 0302 clinical medicine Genotype Genetics medicine Humans Gene Genetics (clinical)IFNR Receptors Interferon Genetics medicine.disease Phenotype Heart defect lcsh:Genetics Vascular endothelial growth factor A 030104 developmental biology Settore MED/03 - Genetica Medica 030220 oncology & carcinogenesis Multigene Family heart defects Female Chromosome 21 SNPs

description

Background: Congenital heart defects (CHDs) are present in about 40&ndash

year	journal	country	edition	language
2020-11-28	Genes

10.3390/genes11121428 http://europepmc.org/articles/PMC7761327

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