6533b834fe1ef96bd129ceae

RESEARCH PRODUCT

Densely PEGylated polybenzofulvene brushes for potential applications in drug encapsulation

Marco PaolinoFederica CastriconiMariano LicciardiSandro DattiloGermano GiulianiMaurizio CanettiMariangela GentileRaniero MendichiAndrea CappelliCinzia ScialabbaDaniele PiovaniAlessandro DonatiEugenio PaccagniniAnnalisa RealeGiorgio GrisciGianluca GiorgiClaudia BonechiFilippo SamperiAntonella Caterina Boccia

subject

Materials scienceBiocompatibilityDrug delivery systemlcsh:RS1-441Pharmaceutical ScienceNanotechnology02 engineering and technology010402 general chemistry01 natural sciencesArticlelcsh:Pharmacy and materia medicachemistry.chemical_compounddrug delivery systemsAffinity polymerization; Drug delivery systems; Grafting onto; Nanocarrier; PEGylation; Polybenzofulvene; Spontaneous polymerization;grafting ontoSide chainaffinity polymerizationPEGylation021001 nanoscience & nanotechnologyGrafting0104 chemical sciencesMonomerchemistryPolymerizationspontaneous polymerizationPEGylationnanocarrierNanocarriersPolybenzofulvene0210 nano-technologypolybenzofulvene;Ethylene glycol

description

The technique of grafting side chains onto a linear polymeric backbone is commonly used to confer to the new polymeric material with desired properties, such as tunable solubility, ionic charge, biocompatibility, or specific interactions with biological systems. In this paper, two new polybenzofulvene backbones were assembled by spontaneous polymerization of the appropriate benzofulvene monomers (4,6-PO-BF3k and 4&rsquo

yearjournalcountryeditionlanguage
2018-11-15
10.3390/pharmaceutics10040234https://publications.cnr.it/doc/396534