6533b834fe1ef96bd129d550

RESEARCH PRODUCT

Alkaloids from Rauwolfia serpentina cell cultures treated with ajmaline

Norio AimiNorio AimiSusanne EndreßHiromitsu TakayamaHiromitsu TakayamaMariko KitajimaMariko KitajimaShin-ichiro SakaiShin-ichiro SakaiJoachim StöckigtShinya SudaShinya Suda

subject

chemistry.chemical_classificationendocrine systemorganic chemicalsCellPlant ScienceGeneral MedicineHorticultureBiologycomplex mixturesBiochemistryAjmalinechemistry.chemical_compoundmedicine.anatomical_structureEnzymeBiosynthesischemistryBiochemistryCell culturemedicineheterocyclic compoundsMolecular Biologymedicine.drug

description

Abstract A group of new alkaloids, the raumaclines, and some related alkaloids were isolated from Rauwolfia serpentina cell suspensions fed with high levels of ajmaline; their structures were determined and syntheses developed providing an essential prerequisite to the further study of their biosynthesis at the enzymatic level.

https://doi.org/10.1016/s0031-9422(00)95161-6