VEGF receptor signaling links inflammation and tumorigenesis in colitis-associated cancer.

6533b834fe1ef96bd129d595

RESEARCH PRODUCT

VEGF receptor signaling links inflammation and tumorigenesis in colitis-associated cancer.

Andre Jefremow Stefan Wirtz Stefan Wirtz Stefan Rose John Markus F. Neurath Markus F. Neurath Raja Atreya Christoph Becker Christoph Becker Moritz Warntjen Maximilian J. Waldner Benno Weigmann Benno Weigmann Clemens Neufert Michael Vieth

subject

Vascular Endothelial Growth Factor A Colorectal cancer Gene Expression medicine.disease_cause chemistry.chemical_compound Mice 0302 clinical medicine Immunology and Allergy Decoy receptors Cells Cultured Mice Knockout 0303 health sciences Microscopy Confocal Reverse Transcriptase Polymerase Chain Reaction Dextran Sulfate respiratory system Colitis Immunohistochemistry 3. Good health Up-Regulation Vascular endothelial growth factor Vascular endothelial growth factor A 030220 oncology & carcinogenesis Colonic Neoplasms cardiovascular system circulatory and respiratory physiology Signal Transduction STAT3 Transcription Factor Immunology Blotting Western Mice Transgenic Biology Article 03 medical and health sciences medicine Animals Humans 030304 developmental biology Cell Proliferation Vascular Endothelial Growth Factor Receptor-1 Cancer Endothelial Cells Kinase insert domain receptor Epithelial Cells Cell Biology medicine.disease Inflammatory Bowel Diseases Vascular Endothelial Growth Factor Receptor-2 Mice Inbred C57BL HIF1A chemistry Cancer research Carcinogenesis 030215 immunology

description

Inflammation drives expression of VEGFR2, which is expressed on and drives growth of tumor cells in colitis-associated cancer.

year	journal	country	edition	language
2010-11-25	The Journal of experimental medicine

10.1084/jem.20100438 https://pubmed.ncbi.nlm.nih.gov/21098094

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