6533b834fe1ef96bd129d69c
RESEARCH PRODUCT
Diagnostic implications of intrapatient genetic tumor heterogeneity
Rosa NogueraAna P. BerbegallSamuel Navarrosubject
0301 basic medicineGeneticsCancer ResearchBiologymedicine.diseaseTumor heterogeneityIntratumoral Genetic Heterogeneity03 medical and health sciences030104 developmental biology0302 clinical medicine030220 oncology & carcinogenesisNeuroblastomamedicineMolecular MedicineAuthor's ViewGenetic compositiondescription
The complex genetic composition of neuroblastoma emphasizes the importance of conscientious and meticulous diagnosis. Clones with amplification or segmental chromosomal aberrations sometimes remain hidden. Several determinations should be performed when sufficient tumor material is available to establish the final diagnosis by combining the results of different techniques on tumor fragments or liquid biopsies.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2015-09-11 |