6533b834fe1ef96bd129d877

RESEARCH PRODUCT

Fast extraction of cannabinoids in marijuana samples by using hard-cap espresso machines

Sergio ArmentaMiguel De La GuardiaLorenzo ColomoKristiina LeimanFrancesc A. Esteve-turrillas

subject

Detection limitTime FactorsChromatographyCannabinoidsIon-mobility spectrometry010401 analytical chemistryExtraction (chemistry)Chemical FractionationCoffee01 natural sciencesGas Chromatography-Mass Spectrometry0104 chemical sciencesAnalytical Chemistry03 medical and health scienceschemistry.chemical_compoundEspresso0302 clinical medicinechemistryδ 9 tetrahydrocannabinolCannabinolHumans030216 legal & forensic medicineGas chromatography–mass spectrometryCannabis

description

Abstract A simple, quick and low cost procedure was developed for the extraction of Δ9-tetrahydrocannabinol, cannabidiol, and cannabinol from marijuana samples, based on the use of a hard-cap espresso extraction with 2-propanol. After extraction, cannabinoids were directly determined after appropriate dilution by gas-chromatography-mass spectrometry, reaching a limit of detection from 0.03 to 0.05 mg g−1. Extraction efficiency was evaluated by the comparison of results obtained for seized samples by the proposed method and a reference methodology based on ultrasound-assisted extraction. Moreover, ion mobility was proposed for the rapid and sensitive determination of Δ9-tetrahydrocannabinol and cannabidiol providing a quick response for the analysis of seized marijuana samples in 1 min, including extraction, dilution and determination.

yearjournalcountryeditionlanguage
2018-03-28Talanta
https://doi.org/10.1016/j.talanta.2018.08.009