6533b834fe1ef96bd129d8b1
RESEARCH PRODUCT
Acidic Co-Catalysts in Cationic Gold Catalysis.
Bo XuGerald B. HammondZhichao LuManish KumarJunbin HanPablo Barriosubject
inorganic chemicals010405 organic chemistryChemistryorganic chemicalsOrganic ChemistryCationic polymerizationGeneral Chemistry010402 general chemistry01 natural sciencesCatalysis0104 chemical sciencesCatalysisReaction rateTransition metalOrganic chemistryheterocyclic compoundsLewis acids and basesBrønsted–Lowry acid–base theorydescription
A systematic study on the effects of Lewis or Bronsted acid co-catalysts in gold-catalyzed reactions was undertaken using representative reactions (O-, N-, and C-nucleophilic additions to alkynes). Through these reactions, it was demonstrated that an acidic co-catalyst can increase the catalyst turnover significantly, enabling practical reaction rates at competitive catalyst loadings (<1 mol %). Further investigation is currently underway to improve the understanding of the subtle principles underlying these experimental observations.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2016-07-22 | Chemistry (Weinheim an der Bergstrasse, Germany) |