6533b834fe1ef96bd129d8b4
RESEARCH PRODUCT
Differentiation of seborrheic keratosis from basal cell carcinoma, nevi and melanoma by RGB autofluorescence imaging
Alexey LihachevIlze LihacovaEmilija Vija PlorinaAlexander DerjaboMarta LangeJanis Spigulissubject
Seborrheic keratosisPathologymedicine.medical_specialty01 natural sciencesArticle010309 opticsLesion030207 dermatology & venereal diseases03 medical and health sciences0302 clinical medicine0103 physical sciencesmedicinePigmented NevusBasal cellBasal cell carcinomaneoplasmsintegumentary systembusiness.industryMelanomamedicine.diseaseAtomic and Molecular Physics and OpticsAutofluorescencemedicine.symptomSkin lesionbusinessBiotechnologydescription
A clinical trial on the autofluorescence imaging of skin lesions comprising 16 dermatologically confirmed pigmented nevi, 15 seborrheic keratosis, 2 dysplastic nevi, histologically confirmed 17 basal cell carcinomas and 1 melanoma was performed. The autofluorescence spatial properties of the skin lesions were acquired by smartphone RGB camera under 405 nm LED excitation. The diagnostic criterion is based on the calculation of the mean autofluorescence intensity of the examined lesion in the spectral range of 515 nm–700 nm. The proposed methodology is able to differentiate seborrheic keratosis from basal cell carcinoma, pigmented nevi and melanoma. The sensitivity and specificity of the proposed method was estimated as being close to 100%. The proposed methodology and potential clinical applications are discussed in this article.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2018-03-23 |