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RESEARCH PRODUCT

Bronchial responsiveness and airway inflammation in trained subjects

Nicola ScichiloneGiuseppe MoriciGiuseppe MoriciMaria R. BonsignoreMaria R. Bonsignore

subject

Pulmonary and Respiratory Medicineeducation.field_of_studybusiness.industryPopulationAirway inflammationPhysical activityrespiratory systemImmunologyLower prevalenceMedicinebusinessAirwayeducationTrained subjectsLung functionBronchial hyperreactivity

description

We read with interest the paper by Shaaban and coworkers1 on the protective effect of physical activity against bronchial hyperreactivity (BHR) in the general population. The authors suggest that a beneficial effect of deep inspirations during exercise could account for the lower prevalence of BHR in physically active subjects compared with sedentary subjects, while the accompanying editorial2 favours an “anti-inflammatory” effect of exercise as the most plausible explanation. We have studied lung function and airway cell biology …

https://doi.org/10.1136/thx.2007.084855