6533b834fe1ef96bd129dfc1

RESEARCH PRODUCT

Pathophysiology of Tumors in Hyperthermia

F. KallinowskiPeter VaupelMatthew A. Kluge

subject

Hyperthermiabusiness.industryIn vivoCancer researchMedicineDistribution (pharmacology)Context (language use)Blood flowbusinessmedicine.diseasePathophysiologyIn vitroMicrocirculation

description

The response of tumor cells to hyperthermia is critically influenced by a number of pathophysiological factors both in vitro and in vivo. The most relevant factors in this context are tumor blood flow, tissue oxygenation, the energy status, and the pH distribution, which in turn define the cellular microenvironment.

https://doi.org/10.1007/978-3-642-83260-4_9