6533b834fe1ef96bd129e059

RESEARCH PRODUCT

Burkholderia cepacia septicemia in a patient with acute myeloid leukemia in postchemotherapy bone marrow aplasia

Romeo-gabriel MihailaLucian Blaga

subject

Acute myeloid leukemiabiologymedicine.diagnostic_testbusiness.industrymedicine.drug_classAntibioticsMyeloid leukemiaCeftazidimeContext (language use)Case ReportGeneral MedicineBone Marrow AplasiaBurkholderia cepaciabiology.organism_classificationCeftazidimeMicrobiologyCotrimoxazoleBurkholderiaImmunologyMedicinebacteriaBlood culturebusinessBacteriamedicine.drug

description

The patients with hematologic malignancies are predisposed to develop infections with unusual bacteria, like Burkholderia cepacia, which is frequently resistant to many antibiotics and antiseptics. We present the case of a female patient with acute myeloid leukemia type 2 on the background of myelodysplastic syndrome, from whom Burkholderia cepacia was isolated in blood culture, after the 2(nd) cycle of induction. She was sensitive to ceftazidime, but its eradication was not easy. Five other patients were contaminated with this bacteria, but all of them had favourable evolution. The case is discussed in the context of those similar in literature.

http://europepmc.org/articles/PMC3858923