6533b834fe1ef96bd129e1f6

RESEARCH PRODUCT

Relationship between rhinitis duration and worsening of nasal function

Angela PistorioGiorgio CiprandiStefania La GruttaIgnazio Cirillo

subject

Nasal Cavity; Nasal Obstruction; Airway Resistance; Humans; Respiration; Rhinomanometry; Cross-Sectional Studies; Rhinitis Allergic Perennial; Rhinitis Allergic Seasonal; Adult; Cohort Studies; Time Factors; Female; MaleAdultMaleNasal cavityTime FactorsRhinitis Allergic PerennialTime FactorCross-sectional studyCohort StudiesAirway resistancemedicineHumansAsthmaCross-Sectional Studiemedicine.diagnostic_testbusiness.industryAirway ResistanceRespirationRhinitis Allergic Seasonalmedicine.diseaseRhinomanometryCross-Sectional Studiesmedicine.anatomical_structureOtorhinolaryngologyAnesthesiaCohortFemaleSurgeryNasal CavityNasal ObstructionCohort StudieRhinomanometrybusinessAirwayHumanCohort study

description

BackgroundWhile it is well known that asthma is characterized by airway remodeling, few studies instead have investigated this issue in patients with allergic rhinitis (AR).ObjectiveThe aim of the study was to evaluate nasal function, ie, nasal airflow, in a cohort of patients with persistent AR (PER).MethodsOne hundred patients, 50 with short-term and 50 with long-term PER, were prospectively and consecutively evaluated, clinically evaluated by visit, skin prick test, and rhinomanometry.ResultsNasal airflow values were significantly lower (median flow: 348 mL/sec) in patients with long-term rhinitis (median duration nine years) as compared to patients with short-term (median duration one year) rhinitis (median flow: 466 mL/sec) (P < 0.0001).ConclusionThis study provides the first evidence that patients with PER may show a progressive worsening of nasal airflow depending on the duration of the disorder.

yearjournalcountryeditionlanguage
2008-06-01Otolaryngology–Head and Neck Surgery
https://doi.org/10.1016/j.otohns.2008.03.027