6533b834fe1ef96bd129e32e
RESEARCH PRODUCT
The influence of personality on the effect of iTBS after being stressed on cortisol secretion
Alicia SalvadorChris BaekenRudi De RaedtJohan SchiettecatteEllen AnckaertMatias M. PulopulosSara De WitteMarie-anne Vanderhasseltsubject
MaleTRANSCRANIAL MAGNETIC STIMULATIONSALIVARY CORTISOLHydrocortisonePhysiologymedicine.medical_treatmentEmotionsIndividualitySocial SciencesHF-RTMS SESSIONPREFRONTAL CORTEXBiochemistryCortisol0302 clinical medicineMedicine and Health SciencesTrier social stress testPsychologyLipid Hormonesmedia_commonBrain MappingCross-Over StudiesMultidisciplinaryDepressionQRGeneral MedicineTranscranial Magnetic StimulationHealthy VolunteersElectrophysiologyBioassays and Physiological AnalysisBrain ElectrophysiologyMedicineFemaleGeneral Agricultural and Biological SciencesPsychologyResearch ArticlePersonalityClinical psychologyAdultCortisol secretionSEX-DIFFERENCESSciencePSYCHOSOCIAL STRESSmedia_common.quotation_subjectPsychological StressNeurophysiologyPrefrontal CortexGenetics and Molecular BiologyResearch and Analysis MethodsAffect (psychology)Young Adult03 medical and health sciencesMental Health and Psychiatry5-FACTOR MODELmedicineHumansPersonalityTranscranial StimulationSalivaSecretionPersonality TraitsSteroid HormonesMood DisordersUNDER-THE-CURVEElectrophysiological TechniquesCooperativenessBiology and Life SciencesMAJOR DEPRESSIONHormones030227 psychiatryTranscranial magnetic stimulationAffectMoodGeneral BiochemistryTemperament and Character InventoryPITUITARY-ADRENAL AXISPhysiological ProcessesStress Psychological030217 neurology & neurosurgeryNeurosciencedescription
Over the last years, individualization of repetitive Transcranial Magnetic Stimulation (rTMS) parameters has been a focus of attention in the field of non-invasive stimulation. It has been proposed that in stress-related disorders personality characteristics may influence the clinical outcome of rTMS. However, the underlying physiological mechanisms as to how personality may affect the rTMS response to stress remains to be clarified. In this sham-controlled crossover study, after being stressed by the Trier Social Stress Test, 38 healthy females received two sessions of intermittent theta burst stimulation (iTBS) applied to the left dorsolateral prefrontal cortex. To take possible personality influences into account, they also completed the Temperament and Character Inventory. Mood and salivary cortisol were assessed throughout the experimental protocol. Overall, two iTBS sessions did not significantly alter mood or influenced cortisol secretion. When taking into account personality features, higher scores on the character dimension Cooperativeness was related to decreased cortisol output, only when active iTBS was administered after the social stressor. In line with other studies, personality features such as the character dimension Cooperativeness may be of particular interest to explain individual neurobiological responses to neurostimulation.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2019-01-01 |