6533b835fe1ef96bd129e8f6

RESEARCH PRODUCT

Triazolopyridines. Part 25: Synthesis of new chiral ligands from [1,2,3]triazolo[1,5-a]pyridines

Belén AbarcaRafael BallesterosFrançoise ColobertFrédéric R. LerouxRafael Ballesteros-garridoRafael Ballesteros-garrido

subject

StereochemistryChemistryOrganic ChemistryDrug DiscoveryTriazolopyridineRing (chemistry)BiochemistryFluorescenceCombinatorial chemistry

description

The synthesis of new chiral triazolopyridine ligands possessing fluorescent properties is described. The triazolo ring opening was studied in order to obtain new chiral 2,6-disubstituted pyridines. A preliminary coordination assay with Zn(II) is also presented.

https://doi.org/10.1016/j.tet.2007.07.101