6533b835fe1ef96bd129e911

RESEARCH PRODUCT

�ber den Einflu� von Mangan-Ionen auf die positiv inotrope Wirkung von Adrenalin, Theophyllin und Digitoxigenin an isolierten Meerschweinchenvorh�fen

H. ScholzT. Meinertz

subject

PharmacologyInotropechemistry.chemical_elementGeneral MedicineManganeseCalciumMedicinal chemistryBivalent (genetics)Digitoxigeninchemistry.chemical_compoundchemistrymedicineExtracellularTheophyllinemedicine.drug

description

The influence of bivalent manganese ions (Mn++) on the positive inotropic effect of adrenaline, theophylline, and digitoxigenin was studied in isolated, electrically driven left guinea-pig auricles in phosphate-free Tyrode's solutions with different extracellular calcium concentrations ([Ca]e; 0.45; 1.8; 7.2 mM).

https://doi.org/10.1007/bf00997146