Impairment of PGC-1 Alpha Up-Regulation Enhances Nitrosative Stress in the Liver during Acute Pancreatitis in Obese Mice

6533b835fe1ef96bd129eb3f

RESEARCH PRODUCT

Impairment of PGC-1 Alpha Up-Regulation Enhances Nitrosative Stress in the Liver during Acute Pancreatitis in Obese Mice

María Monsalve Isabel Torres-cuevas Salvador Pérez Sergio Rius-pérez Francisco J. Miranda

subject

PGC-1&#945 0301 basic medicine obesity medicine.medical_specialty Antioxidant acute pancreatitis Physiology medicine.medical_treatment Clinical Biochemistry PGC-1α Alpha (ethology)Nitrosative stress liver Hepatic Complication Biochemistry Article 03 medical and health sciences 0302 clinical medicine Downregulation and upregulation Internal medicine medicine Obesity Molecular Biology Liver injury business.industry lcsh:RM1-950 Organ dysfunction Cell Biology Biología y Biomedicina / Biología medicine.disease nitrosative stress Acute pancreatitis lcsh:Therapeutics. Pharmacology 030104 developmental biology Endocrinology Liver 030220 oncology & carcinogenesis Pancreatitis Acute pancreatitis medicine.symptom business

description

Acute pancreatitis is an inflammatory process of the pancreatic tissue that often leads to distant organ dysfunction. Although liver injury is uncommon in acute pancreatitis, obesity is a risk factor for the development of hepatic complications. The aim of this work was to evaluate the role of PGC-1&alpha

year	journal	country	edition	language
2020-09-19	Antioxidants

10.3390/antiox9090887 http://dx.doi.org/10.3390/antiox9090887

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