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RESEARCH PRODUCT
Whole-genome characterization of Shewanella algae strain SYT3 isolated from seawater reveals insight into hemolysis.
Yu-kai HongShi-yu ChenAlexander MenzerJan Fang ChengShu-peng HoZong-yen WuZong-yen WuKwong-chung TungYao-ting HuangYing-ju ChenPo-yu Liusubject
0301 basic medicineMicrobiology (medical)DNA BacterialShewanellaOperon030106 microbiologyTaiwanShewanella algaeMicrobial Sensitivity TestsMicrobiologyGenomeHemolysisbeta-LactamasesMicrobiology03 medical and health sciencesHemolysin ProteinsAntibiotic resistanceAlgaeBacterial ProteinsRNA Ribosomal 16SDrug Resistance BacterialmedicineHumansSeawaterGenePhylogenyWhole genome sequencingbiologyWhole Genome SequencingChromosome Mappingbiology.organism_classificationmedicine.diseaseHemolysisAnti-Bacterial AgentsBacterial Typing TechniquesGenome Bacterialdescription
Aim: To describe the genomic characteristics of seawater-borne hemolytic Shewanella algae and its resistance genes. Materials & methods: Whole genome sequence of S. algae SYT3 was determined using llumina MiSeq platform. Multiple-database-based analysis was performed to identify the genetic background of its hemolytic activity and the antibiotic resistance genes. Results: S. algae SYT3 possesses a homolog of the hly operon involved in the synthesis of hemolysin. We also identified candidate genes associated with resistance to β-lactam antibiotics (bla OXA-55) and fluoroquinolone (qnrA3). Conclusion: The study provides an insight into the hemolytic activity of S. algae. Our findings also suggested S. algae as a potential reservoir of antimicrobial resistance determinants.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2018-12-01 | Future microbiology |