6533b835fe1ef96bd129ebfd
RESEARCH PRODUCT
Self-assembly of a bioelastomeric structure: solution dynamics and the spinodal and coacervation lines.
F. SciortinoDan W. UrryKari U. PrasadM. U. Palmasubject
SpinodalPhase transitionChemical PhenomenaLightStereochemistryMolecular Sequence DataBiophysicsBiochemistryInstabilityLight scatteringBiomaterialsMolecular dynamicsMetastabilityScattering RadiationAmino Acid SequencePhase diagramQuantitative Biology::BiomoleculesScatteringChemistryChemistry PhysicalOrganic ChemistryTemperatureGeneral MedicineSolutionsChemical physicsPeptidesdescription
The stability, metastability, and instability regions of aqueous solutions of a representative synthetic bioelastomeric polymer, poly (Val-Pro-Gly-Val-Gly), were determined by a combined use of elastic and quasi-elastic light scattering experiments. The approach followed here offers the attractive advantage of singling out the relevant contributions to the total scattering even in the presence of traces of noninteracting larger sized impurities. Conclusions so reached were checked by means of independent experiments. The present results provide descriptions of the very early events in the physics of bioelastogenesis in terms of general polymer science and phase transitions, and in terms of an unexpected possible functional role of density fluctuations.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1990-08-15 | Biopolymers |