6533b835fe1ef96bd129ec8c

RESEARCH PRODUCT

Cross-Sectional Associations between Homoarginine, Intermediate Phenotypes, and Atrial Fibrillation in the Community—The Gutenberg Health Study

Christoph NiekampRenate B. SchnabelPhilipp S. WildThomas MünzelFrancisco OjedaTanja ZellerIrene SchmidtmannManfred E. BeutelBlankenberg StefanDorothee AtzlerNorbert PfeifferKarl J. LacknerRainer H. BögerEdzard SchwedhelmChristoph SinningAnja Leuschner

subject

Male0301 basic medicineCardiac function curvemedicine.medical_specialtyPopulationlcsh:QR1-502030204 cardiovascular system & hematologyBiochemistryArticlelcsh:MicrobiologyElectrocardiography03 medical and health sciences0302 clinical medicineResidence CharacteristicsRisk FactorsInterquartile rangeInternal medicinemedicineHumanshomoarginineatrial fibrillationpopulation-based cohortRisk factoreducationMolecular BiologyAgededucation.field_of_studybusiness.industryAtrial fibrillationOdds ratioMiddle Agedmedicine.diseaseHealth SurveysConfidence interval3. Good healthdiastolic disfunctionCross-Sectional StudiesPhenotype030104 developmental biologyCase-Control StudiesCardiologyBiomarker (medicine)biomarkerFemalebusiness

description

Homoarginine has come into the focus of interest as a biomarker for cardiovascular disease. Atrial fibrillation (AF) causes a substantial increase in morbidity and mortality. Whether circulating homoarginine is associated with occurrence or persistence of AF and may serve as a new predictive biomarker remains unknown. We measured plasma levels of homoarginine in the population-based Gutenberg health study (3761 patients included, of them 51.7% males), mean age 55.6 &plusmn

yearjournalcountryeditionlanguage
2018-08-01Biomolecules
10.3390/biom8030086http://www.mdpi.com/2218-273X/8/3/86