6533b835fe1ef96bd129ecb9

RESEARCH PRODUCT

Mesenchymal Stem Cells in Solid Organ Transplantation (MiSOT) Fourth Meeting

M. FranquesaM.j. HoogduijnM.e. ReindersE. EggenhoferA.u. EngelaF.k. MensahJ. TorrasA. PileggiC. Van KootenB. MahonO. DetryF.c. PoppV. BenselerF. CasiraghiC. JohnsonJ. AncansB. FillenbergO. DelarosaJ.m. AranM. Roemeling-vanrhijnJ. PinxterenN. PericoE. GottiB. ChristJ. ReadingM. IntronaR. DeansM. ShagidulinR. FarreA. RambaldiA. Sanchez-fueyoN. ObermajerA. PulinF.j.m.f. DorI. Portero-sanchezC.c. BaanT.j. RabelinkG. RemuzziM.g.h. BetjesM.h. DahlkeJ.m. GrinyoMisot Study Grp

subject

Oncologymedicine.medical_specialtyTransplantationFuture studiesbusiness.industryMesenchymal stem cellClinical settingsPreclinical dataClinical trialTransplantationImmunomodulationInternal medicineImmunologymedicinePosition paperMesenchymal stem cellsPosition paperSolid organ transplantationbusiness

description

The Fourth Expert Meeting of the Mesenchymal Stem Cells in Solid Organ Transplantation (MiSOT) Consortium took place in Barcelona on October 19 and 20, 2012. This meeting focused on the translation of preclinical data into early clinical settings. This position paper highlights the main topics explored on the safety and efficacy of mesenchymal stem cells as a therapeutic agent in solid organ transplantation and emphasizes the issues (proper timing, concomitant immunossupression, source and immunogenicity of mesenchymal stem cells, and oncogenicity) that have been addressed and will be followed up by the MiSOT Consortium in future studies.

10.1097/tp.0b013e318298f9fahttps://doi.org/10.1097/TP.0b013e318298f9fa