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RESEARCH PRODUCT
A 15-Year Single-Center Experience of Endovascular Repair for Elective and Ruptured Abdominal Aortic Aneurysms
Marc R.h.m. Van SambeekYannick W. ‘T MannetjeJoep A.w. TeijinkPieter P.h.l. BroosRutger A. StokmansGiuseppe CorteSaskia HoutermanPhilippe W.m. Cuyperssubject
MaleTime FactorsDatabases Factualmedicine.medical_treatmentKaplan-Meier Estimate030204 cardiovascular system & hematologySingle CenterEndovascular aneurysm repairendovascular aneurysm repairPostoperative Complications0302 clinical medicineRisk Factors030212 general & internal medicineNetherlandsAged 80 and overmedicine.diagnostic_testruptured aneurysmEndovascular ProceduresMiddle AgedAbdominal aortic aneurysmTreatment OutcomeElective Surgical ProceduresreinterventionsFemaleStentsmedicine.symptomCardiology and Cardiovascular Medicinemedicine.medical_specialtyAortographycomplicationsAortic RuptureendoleakProsthesis DesignAortographyAsymptomaticDisease-Free SurvivalBlood Vessel Prosthesis Implantation03 medical and health sciencesabdominal aortic aneurysmBlood vessel prosthesismedicineHumansRadiology Nuclear Medicine and imagingAortic ruptureAgedRetrospective Studiesstent-graftbusiness.industryRetrospective cohort studymedicine.diseaseBlood Vessel ProsthesisSurgerySurgeryEmergenciesbusinessAortic Aneurysm Abdominaldescription
Purpose: To evaluate the differences in technical outcomes and secondary interventions between elective endovascular aneurysm repair (el-EVAR) procedures and those for ruptured aneurysms (r-EVAR). Methods: Of the 906 patients treated with primary EVAR from September 1998 until July 2012, 43 cases were excluded owing to the use of first-generation stent-grafts. Among the remaining 863 patients, 773 (89.6%) patients (mean age 72 years; 697 men) with asymptomatic or symptomatic abdominal aortic aneurysms (AAAs) were assigned to the el-EVAR group; 90 (10.4%) patients (mean age 73 years; 73 men) were assigned to the r-EVAR group based on blood outside the aortic wall on preoperative imaging. The primary study outcome was technical success; secondary endpoints, including freedom from secondary interventions and late survival, were examined with Kaplan-Meier analyses. Results: At baseline, r-EVAR patients had larger aneurysms on average (p<0.001) compared to el-EVAR patients. Technical success was comparable (p=0.052), but there were more type Ia endoleaks at completion angiography in the r-EVAR group (p=0.038). As anticipated, more patients died in the first month in the r-EVAR group (18.9% vs 2.2% el-EVAR, p<0.001). At 5 years, there was an overall survival of 65.1% for the el-EVAR patients vs 48.1% in the r-EVAR group (p<0.001). The freedom from AAA-related mortality was 95.7% for el-EVAR and 71.0% for r-EVAR (p<0.001). Five-year freedom from type I/III endoleaks was significantly lower in the r-EVAR group (78.7% vs 90.0%, p=0.003). Five-year freedom from secondary intervention estimates were not significantly different (el-EVAR 84.2% vs r-EVAR 78.2%, p=0.064). Conclusion: Within our cohort of primary EVAR patients, r-EVAR cases showed comparable stent-graft–related technical outcome. Although there was a higher incidence of type Ia endoleaks on completion angiography in the r-EVAR group, the overall secondary intervention rate was comparable to el-EVAR.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2016-08-01 | Journal of Endovascular Therapy |