6533b835fe1ef96bd129efdf
RESEARCH PRODUCT
Several 1,3-thiazolidin-4-ones bearing a 2,6-dihalophenyl group at C-2 and a variously substituted phenyl ring at N-3 have been synthesized and tested as anti-HIV agents. The results of the in vitro tests showed that some of them proved to be effective inhibitors of HIV-1 replication.
A RaoA ChimirriE De ClercqA. M MonforteP MonforteC PannecouqueM. ZappalàAnna Carbonesubject
Anti-HIV activity23-Diaryl-13-thiazolidin-4-oneNNRTIsdescription
Several 1,3-thiazolidin-4-ones bearing a 2,6-dihalophenyl group at C-2 and a variously substituted phenyl ring at N-3 have been synthesized and tested as anti-HIV agents. The results of the in vitro tests showed that some of them proved to be effective inhibitors of HIV-1 replication.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2003-01-01 |