6533b835fe1ef96bd129f567

RESEARCH PRODUCT

Sex-specific association of the ST8SIAII gene with schizophrenia in a Spanish population

Javier Gilabert-juanJuan NacherJulio SanjuánMaría Dolores Moltó

subject

MaleGenotypeBiologyPolymorphism Single NucleotideWhite PeopleSex FactorsGenotypemedicineHumansGenetic Predisposition to DiseaseAllelePromoter Regions GeneticAssociation (psychology)GeneAllelesBiological PsychiatryGeneticsHaplotypemedicine.diseaseSex specificSialyltransferasesSpanish populationPsychiatry and Mental healthHaplotypesSpainSchizophreniaSchizophreniaFemale

description

We investigated the association between ST8SIAII and schizophrenia in a sample of Spanish origin. We found that the G allele (P=0.044) and the AG genotype (P=0.040) of rs3759916 were associated in females. The ACAG haplotype (rs3759914, rs3759915, rs3759916 and rs2305561) was associated in males (P=0.028).

https://doi.org/10.1016/j.psychres.2013.09.001