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RESEARCH PRODUCT
Electrospun PCL/GO-g-PEG structures: Processing-morphology-properties relationships
Giulio GhersiSalvatrice RigogliusoLuigi BottaFrancesco LoprestiAndrea MaioRoberto Scaffarosubject
Materials scienceComposite numbermacromolecular substances02 engineering and technology010402 general chemistry01 natural sciencesMultifunctional compositechemistry.chemical_compoundPEG ratioComposite materialtechnology industry and agriculturePEGylated graphene oxideequipment and supplies021001 nanoscience & nanotechnologyGraftingElectrospinning0104 chemical scienceschemistryMechanics of MaterialsNanofiberPolycaprolactoneCeramics and CompositesBiocomposite0210 nano-technologyBiocompositeMechanical propertieEthylene glycoldescription
Abstract Polycaprolactone (PCL) biocomposite nanofiber scaffolds with different concentrations of graphene oxide (GO) and GO surface grafted with poly(ethylene glycol) (GO-g-PEG) were prepared by electrospinning. Morphological, mechanical as well as wettability characterizations of electrospun nanofibers were carried out. Results showed that the average diameter of PLA/GO electrospun nanofibers decreased upon increasing the filler content. Differently, the diameter increased while using GO-g-PEG. Both nanofillers enhanced the electrospun PCL hydrophilicity even if PCL/GO-g-PEG samples exhibited improved wettability. The Young moduli of the composite nanofiber mats were improved by adding GO, and it was further enhanced when GO was surface grafted with PEG, in particular at low concentrations. This suggests the improved dispersion of GO-g-PEG due to the surface grafting with PEG. Furthermore, in order to assess the potential applications of the electrospun nanofibers in tissue engineering, MC3T3-E1 cells were cultured on PCL and PCL/GO-g-PEG scaffolds, thus providing preliminary and comparative proliferation rate assays.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2017-01-01 | Composites Part A: Applied Science and Manufacturing |