6533b836fe1ef96bd12a08c7

RESEARCH PRODUCT

Leucocyte- and Platelet-Rich Fibrin Block: Its Use for the Treatment of a Large Cyst with Implant-Based Rehabilitation

Luca FiorilloViviana De CaroDenise MurgiaOrazio CiceroRodolfo MauceriRodolfo MauceriLuigi PaternòGiuseppina Campisi

subject

medicine.medical_specialtyMedicine (General)odontogenic cystplatelet-rich fibrin02 engineering and technologyBone healingLarge cyst03 medical and health sciences0302 clinical medicineR5-920Odontogenic cystbone regenerationPRF blockmedicinecase reportCystBone regenerationDental alveolusbusiness.industry030206 dentistryGeneral Medicine021001 nanoscience & nanotechnologymedicine.diseasePlatelet-rich fibrindigestive system diseasesSurgeryImplant0210 nano-technologybusinessPRF

description

The management of critical-size bone defects is still demanding. Recently, autologous platelet concentrates in combination with bone substitute have been applied and reported in a few studies. Our aim is to report the healing of a critical-size alveolar bone defect treated with a new bone regeneration technique by means of L-PRF and L-PRF blocks. A 45-year-old woman presented a large cystic lesion; the extraction of three teeth, a cyst removal procedure, and bone regeneration procedures with L-PRF and L-PRF blocks were planned. The L-PRF block was prepared by mixing a bone substitute with a piece of L-PRF membrane and liquid fibrinogen. Additionally, after bone healing an implant-based rehabilitation was optimally performed. On the basis of the positive results, in terms of bone healing and tissue regeneration in a large bone defect, the application of L-PRF and L-PRF blocks, in agreement with the scarce literature, is suggested as a feasible procedure in selected cases.

yearjournalcountryeditionlanguage
2021-02-01Medicina
10.3390/medicina57020180https://www.mdpi.com/1010-660X/57/2/180