6533b836fe1ef96bd12a0bd2
RESEARCH PRODUCT
Jejunoileal bypass as the main procedure in the onset of immune-related conditions: the model of BADAS
Francesco CicciaIlenia PantanoGiovani TrioloVasiliki LiakouliFrancesco CarubbiGianfranco AmicucciPaola CiprianiPiero RuscittiAntonio GiulianiPaola Di BenedettoSaverio AlvaroFederica PiccioneRoberto Giacomellisubject
Short Bowel Syndromemedicine.medical_specialtyPediatricsmedicine.medical_treatmentJejunoileal bypass immune-related conditionsImmunologyJejunoileal bypassSkin DiseasesGastroenterologyImmune systemBlind loop syndromeJejunoileal BypassInternal medicinemedicineHumansImmunology and AllergyIn patientIntestinal bypassbusiness.industryBowel-associated dermatosis–arthritis syndromeArthritismedicine.diseaseCaloric intakeimmune-related conditionsBlind Loop SyndromeComplicationbusinessJejunoileal bypadescription
Bariatric surgery represents a common approach for the control of severe morbid obesity, reducing caloric intake by modifying the anatomy of the gastrointestinal tract. Following jejunoileal bypass, a large spectrum of complications has been described, with rheumatic manifestation present in up to 20% of cases. Although bowel bypass syndrome, also called blind loop syndrome, is a well-recognized complication of jejunoileal bypass, the same syndrome was recognized in patients who had not had intestinal bypass surgery, and the term the 'bowel-associated dermatosis-arthritis syndrome' (BADAS) was coined. The pathogenesis of BADAS is as yet poorly understood and only few data concerning this issue have been published in the literature. The aim of the present paper is to review the literature and to discuss putative pathogenic mechanisms of BADAS, focusing on the immune system.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2013-01-01 |