6533b836fe1ef96bd12a12d7

RESEARCH PRODUCT

Modeling of growth and lactate fermentation by Lactococcus lactis subsp. lactis biovar. diacetylactis in batch culture

Charles DivièsRémy Cachon

subject

BiovarLactococcus lactisfood and beveragesGeneral MedicineBiologybiology.organism_classificationStreptococcaceaeApplied Microbiology and BiotechnologyLactococcus lactis subsp. lactisBiochemistryProduct formationFermentationLactic acid fermentationBacteriaBiotechnology

description

The kinetic behaviour of Lactococcus lactis subsp. lactis biovar. diacetylactis was studied in batch culture under non-limiting conditions that allow high growth and product formation. A model based on laboratory results is proposed for growth and l-lactate fermentation. It shows the necessity for differentiating biomass into three physiological states, two active, Xg (growth + acidification) and Xng (acidification), and one inactive, Xi. The kinetic theory of the model demonstrates the non-competitive nature of fermentation end-product inhibition on growth and acidification, and describes the passage from one physiological state to another. Satisfying simulations were obtained for batch fermentations, and the use of this type of model for determining and optimizing fermentation parameters is discussed.

https://doi.org/10.1007/bf00170424