6533b836fe1ef96bd12a131a

RESEARCH PRODUCT

Screening of tropical medicinal plants for antiinflammatory activity

María-carmen RecioSalvador MáñezAndrew MarstonKurt HostettmannRosa-maría GinerJosé-luis Ríos

subject

Pharmacologyfood.ingredientbiologyTraditional medicineClusiaceaeDiospyrosbiology.organism_classificationMoraceaefoodSimaroubaceaeMedicinal plantsHypericumEbenaceaeHeteromorpha

description

The antiinflammatory activity of different extracts from 16 tropical plant species belonging to 15 different families has been determined. They were administered topically on TPA-induced mouse ear oedema and orally on carrageenan-induced mouse paw oedema. In the latter, extracts from Diospyros leucomelas, Erythrospermum monticolumn, Ficus polita, Heteromorpha trifoliata, Hypericum lalandii, Kirkia acuminata, Pterocarpus angolensis and Zanha africana significantly reduced the oedema 3 h after carrageenan injection. All the extracts were considerably active when assayed topically with only three exceptions.

https://doi.org/10.1002/ptr.2650090807