6533b836fe1ef96bd12a15ee

RESEARCH PRODUCT

RADICAL DISTRIBUTIONS IN AMMONIUM TARTRATE SINGLE CRYSTALS EXPOSED TO PHOTON AND NEUTRON BEAMS

Antonio BarbonAntonio BarbonMaurizio MarraleMaria BraiAnna LongoMarina BrustolonMarina Brustolon

subject

Materials sciencePhotonFree RadicalsTrack nanodosimetryLinear energy transferElectronsRadiationMolecular physicsIonizing radiationMagneticsRadiation IonizingRadiology Nuclear Medicine and imagingHeavy IonsIrradiationCobalt RadioisotopesRadiometryTartratesNeutronsRange (particle radiation)PhotonsRadiationRadiological and Ultrasound TechnologyRadiation induced radicals ammonium tartrate pulsed electron paramagnetic resonanceelectron spin resonancePublic Health Environmental and Occupational HealthElectron Spin Resonance SpectroscopyGeneral MedicineCharged particleNeutron temperatureSettore FIS/07 - Fisica Applicata(Beni Culturali Ambientali Biol.e Medicin)CarbonGamma RaysTrack nanodosimetry; electron spin resonanceCrystallization

description

The radiation therapy carried out by means of heavy charged particles (such as carbon ions) and neutrons is rapidly becoming widespread worldwide. The success of these radiation therapies relies on the high density of energy released by these particles or by secondary particles produced after primary interaction with matter. The biological damages produced by ionising radiations in tissues and cells depend more properly on the energy released per unit pathlength, which is the linear energy transfer and which determines the radiation quality. To improve the therapy effectiveness, it is necessary to grasp the mechanisms of free radical production and distribution after irradiation with these particles when compared with the photon beams. In this work some preliminary results on the analysis of the spatial distributions of the free radicals produced after exposure of ammonium tartrate crystals to various radiation beams ((60)Co gamma photons and thermal neutrons) were reported. Electron spin resonance analyses were performed by the electron spin echo technique, which allows the determination of local spin concentrations and by double electron-electron resonance technique, which is able to measure the spatial distance distribution (range 1.5-8 nm) among pairs of radicals in solids. The results of these analyses are discussed on the basis of the different distributions of free radicals produced by the two different radiation beams used.

10.1093/rpd/ncu033http://hdl.handle.net/11577/2899700